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Species Differences in Alternative Substrate Utilization by the Antibacterial Target Undecaprenyl Pyrophosphate Synthase

[Image: see text] Undecaprenyl pyrophosphate synthase (UPPS) is a critical enzyme required for the biosynthesis of polysaccharides essential for bacterial survival. In this report, we have tested the substrate selectivity of UPPS derived from the mammalian symbiont Bacteroides fragilis, the human pa...

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Detalles Bibliográficos
Autores principales: Dodbele, Samantha, Martinez, Christina D., Troutman, Jerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341984/
https://www.ncbi.nlm.nih.gov/pubmed/25020247
http://dx.doi.org/10.1021/bi500545g