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Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons

The anaphase-promoting complex/cyclosome (APC/C) controls a variety of cellular processes through its ability to target numerous protein substrates for timely degradation. Substrate selection by this ubiquitin ligase depends on related activator proteins, Cdc20 and Cdh1, which bind and activate the...

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Detalles Bibliográficos
Autores principales: Arnold, Lea, Höckner, Sebastian, Seufert, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342022/
https://www.ncbi.nlm.nih.gov/pubmed/25540434
http://dx.doi.org/10.1091/mbc.E14-09-1342