Cargando…

Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process

Recent studies have investigated the dendritic actin cytoskeleton of the cell edge's lamellipodial (LP) region by experimentally decreasing the activity of the actin filament nucleator and branch former, the Arp2/3 complex. Here we extend these studies via pharmacological inhibition of the Arp2...

Descripción completa

Detalles Bibliográficos
Autores principales: Henson, John H., Yeterian, Mesrob, Weeks, Richard M., Medrano, Angela E., Brown, Briana L., Geist, Heather L., Pais, Mollyann D., Oldenbourg, Rudolf, Shuster, Charles B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342025/
https://www.ncbi.nlm.nih.gov/pubmed/25568343
http://dx.doi.org/10.1091/mbc.E14-07-1244