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CLASP2-dependent microtubule capture at the neuromuscular junction membrane requires LL5β and actin for focal delivery of acetylcholine receptor vesicles

A hallmark of the neuromuscular junction (NMJ) is the high density of acetylcholine receptors (AChRs) in the postsynaptic muscle membrane. The postsynaptic apparatus of the NMJ is organized by agrin secreted from motor neurons. The mechanisms that underlie the focal delivery of AChRs to the adult NM...

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Detalles Bibliográficos
Autores principales: Basu, Sreya, Sladecek, Stefan, Martinez de la Peña y Valenzuela, Isabel, Akaaboune, Mohammed, Smal, Ihor, Martin, Katrin, Galjart, Niels, Brenner, Hans Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342029/
https://www.ncbi.nlm.nih.gov/pubmed/25589673
http://dx.doi.org/10.1091/mbc.E14-06-1158