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Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages

Membrane remodeling in the early stages of phagocytosis enables the engulfment of particles or pathogens and receptor signaling to activate innate immune responses. Members of the Rab GTPase family and their disparate effectors are recruited sequentially to regulate steps throughout phagocytosis. Ra...

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Detalles Bibliográficos
Autores principales: Yeo, Jeremy C., Wall, Adam A., Luo, Lin, Stow, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342030/
https://www.ncbi.nlm.nih.gov/pubmed/25568335
http://dx.doi.org/10.1091/mbc.E14-10-1457