A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail

BACKGROUND: Plasmodium falciparum is the most pathogenic of the human malaria parasite species and a major cause of death in Africa. It’s resistance to most of the current drugs accentuates the pressing need for new chemotherapies. Polyamine metabolism of the parasite is distinct from the human path...

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Detalles Bibliográficos
Autores principales: Burger, Pieter B, Williams, Marni, Sprenger, Janina, Reeksting, Shaun B, Botha, Mariëtte, Müller, Ingrid B, Joubert, Fourie, Birkholtz, Lyn-Marie, Louw, Abraham I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342090/
https://www.ncbi.nlm.nih.gov/pubmed/25651815
http://dx.doi.org/10.1186/s12936-015-0572-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342090/
https://www.ncbi.nlm.nih.gov/pubmed/25651815
http://dx.doi.org/10.1186/s12936-015-0572-z

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