Targeting adipose tissue via systemic gene therapy

Adipose tissue plays a critical role in energy and metabolic homeostasis, but it is challenging to adapt techniques to modulate adipose function in vivo. Here we develop an in vivo, systemic method of gene transfer specifically targeting adipose tissue using adeno-associated virus (AAV) vectors. We...

Descripción completa

Detalles Bibliográficos
Autores principales: O'Neill, Sean M., Hinkle, Christine, Chen, Shu-Jen, Sandhu, Arbansjit, Hovhannisyan, Ruben, Stephan, Stephen, Lagor, William R., Ahima, Rexford S., Johnston, Julie C., Reilly, Muredach P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342115/
https://www.ncbi.nlm.nih.gov/pubmed/24830434
http://dx.doi.org/10.1038/gt.2014.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342115/
https://www.ncbi.nlm.nih.gov/pubmed/24830434
http://dx.doi.org/10.1038/gt.2014.38

Ejemplares similares