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Whole Genome Sequencing Based Characterization of Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from Pakistan

Improved molecular diagnostic methods for detection drug resistance in Mycobacterium tuberculosis (MTB) strains are required. Resistance to first- and second- line anti-tuberculous drugs has been associated with single nucleotide polymorphisms (SNPs) in particular genes. However, these SNPs can vary...

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Detalles Bibliográficos
Autores principales: Ali, Asho, Hasan, Zahra, McNerney, Ruth, Mallard, Kim, Hill-Cawthorne, Grant, Coll, Francesc, Nair, Mridul, Pain, Arnab, Clark, Taane G., Hasan, Rumina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342168/
https://www.ncbi.nlm.nih.gov/pubmed/25719196
http://dx.doi.org/10.1371/journal.pone.0117771