Synergistic Activations of REG Iα and REG I β Promoters by IL-6 and Glucocorticoids through JAK/STAT Pathway in Human Pancreatic β Cells

Reg (Regenerating gene) gene was originally isolated from rat regenerating islets and its encoding protein was revealed as an autocrine/paracrine growth factor for β cells. Rat Reg gene is activated in inflammatory conditions for β cell regeneration. In human, although five functional REG family gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamauchi, Akiyo, Itaya-Hironaka, Asako, Sakuramoto-Tsuchida, Sumiyo, Takeda, Maiko, Yoshimoto, Kiyomi, Miyaoka, Tomoko, Fujimura, Takanori, Tsujinaka, Hiroki, Tsuchida, Chikatsugu, Ota, Hiroyo, Takasawa, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342170/
https://www.ncbi.nlm.nih.gov/pubmed/25767811
http://dx.doi.org/10.1155/2015/173058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342170/
https://www.ncbi.nlm.nih.gov/pubmed/25767811
http://dx.doi.org/10.1155/2015/173058

Ejemplares similares