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Synergistic Activations of REG Iα and REG I β Promoters by IL-6 and Glucocorticoids through JAK/STAT Pathway in Human Pancreatic β Cells
Reg (Regenerating gene) gene was originally isolated from rat regenerating islets and its encoding protein was revealed as an autocrine/paracrine growth factor for β cells. Rat Reg gene is activated in inflammatory conditions for β cell regeneration. In human, although five functional REG family gen...
Autores principales: | Yamauchi, Akiyo, Itaya-Hironaka, Asako, Sakuramoto-Tsuchida, Sumiyo, Takeda, Maiko, Yoshimoto, Kiyomi, Miyaoka, Tomoko, Fujimura, Takanori, Tsujinaka, Hiroki, Tsuchida, Chikatsugu, Ota, Hiroyo, Takasawa, Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342170/ https://www.ncbi.nlm.nih.gov/pubmed/25767811 http://dx.doi.org/10.1155/2015/173058 |
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