Virus-Like Particles Activate Type I Interferon Pathways to Facilitate Post-Exposure Protection against Ebola Virus Infection

Ebola virus (EBOV) causes a severe hemorrhagic disease with high fatality. Virus-like particles (VLPs) are a promising vaccine candidate against EBOV. We recently showed that VLPs protect mice from lethal EBOV infection when given before or after viral infection. To elucidate pathways through which...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayithan, Natarajan, Bradfute, Steven B., Anthony, Scott M., Stuthman, Kelly S., Bavari, Sina, Bray, Mike, Ozato, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342244/
https://www.ncbi.nlm.nih.gov/pubmed/25719445
http://dx.doi.org/10.1371/journal.pone.0118345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342244/
https://www.ncbi.nlm.nih.gov/pubmed/25719445
http://dx.doi.org/10.1371/journal.pone.0118345

Ejemplares similares