Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions

Protein AMPylation, the transfer of AMP from ATP to protein targets, has been recognized as a new mechanism of host-cell disruption by some bacterial effectors that typically contain a FIC-domain. Eukaryotic genomes also encode one FIC-domain protein, HYPE, which has remained poorly characterized. H...

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Detalles Bibliográficos
Autores principales: Bunney, Tom D., Cole, Ambrose R., Broncel, Malgorzata, Esposito, Diego, Tate, Edward W., Katan, Matilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342408/
https://www.ncbi.nlm.nih.gov/pubmed/25435325
http://dx.doi.org/10.1016/j.str.2014.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342408/
https://www.ncbi.nlm.nih.gov/pubmed/25435325
http://dx.doi.org/10.1016/j.str.2014.10.007

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