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Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions
Protein AMPylation, the transfer of AMP from ATP to protein targets, has been recognized as a new mechanism of host-cell disruption by some bacterial effectors that typically contain a FIC-domain. Eukaryotic genomes also encode one FIC-domain protein, HYPE, which has remained poorly characterized. H...
Autores principales: | Bunney, Tom D., Cole, Ambrose R., Broncel, Malgorzata, Esposito, Diego, Tate, Edward W., Katan, Matilda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342408/ https://www.ncbi.nlm.nih.gov/pubmed/25435325 http://dx.doi.org/10.1016/j.str.2014.10.007 |
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