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Cyclosporine A reduces microvascular obstruction and preserves left ventricular function deterioration following myocardial ischemia and reperfusion

Postconditioning and cyclosporine A prevent mitochondrial permeability transition pore opening providing cardioprotection during ischemia/reperfusion. Whether microvascular obstruction is affected by these interventions is largely unknown. Pigs subjected to coronary occlusion for 1 h followed by 3 h...

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Detalles Bibliográficos
Autores principales: Zalewski, Jaroslaw, Claus, Piet, Bogaert, Jan, Driessche, Nina Vanden, Driesen, Ronald B., Galan, Diogo T., Sipido, Karin R., Buszman, Piotr, Milewski, Krzysztof, Van de Werf, Frans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342514/
https://www.ncbi.nlm.nih.gov/pubmed/25720581
http://dx.doi.org/10.1007/s00395-015-0475-8