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Propofol effectively inhibits lithium-pilocarpine- induced status epilepticus in rats via downregulation of N-methyl-D-aspartate receptor 2B subunit expression

Status epilepticus was induced via intraperitoneal injection of lithium-pilocarpine. The inhibitory effects of propofol on status epilepticus in rats were judged based on observation of behavior, electroencephalography and 24-hour survival rate. Propofol (12.5–100 mg/kg) improved status epilepticus...

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Detalles Bibliográficos
Autores principales: Wang, Henglin, Wang, Zhuoqiang, Mi, Weidong, Zhao, Cong, Liu, Yanqin, Wang, Yongan, Sun, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342709/
https://www.ncbi.nlm.nih.gov/pubmed/25737709
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.005