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Low Non-NMDA Receptor Current Density as Possible Protection Mechanism from Neurotoxicity of Circulating Glutamate on Subfornical Organ Neurons in Rats

The subfornical organ (SFO) is one of circumventricular organs characterized by the lack of a normal blood brain barrier. The SFO neurons are exposed to circulating glutamate (60~100 µM), which may cause excitotoxicity in the central nervous system. However, it remains unclear how SFO neurons are pr...

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Detalles Bibliográficos
Autores principales: Chong, Wonee, Kim, Seong Nam, Han, Seong Kyu, Lee, So Yeong, Ryu, Pan Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342738/
https://www.ncbi.nlm.nih.gov/pubmed/25729280
http://dx.doi.org/10.4196/kjpp.2015.19.2.177