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Isotope Effects as Probes for Enzyme Catalyzed Hydrogen-Transfer Reactions

Kinetic Isotope effects (KIEs) have long served as a probe for the mechanisms of both enzymatic and solution reactions. Here, we discuss various models for the physical sources of KIEs, how experimentalists can use those models to interpret their data, and how the focus of traditional models has gro...

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Detalles Bibliográficos
Autores principales: Roston, Daniel, Islam, Zahidul, Kohen, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342783/
https://www.ncbi.nlm.nih.gov/pubmed/23673528
http://dx.doi.org/10.3390/molecules18055543