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Extrapolating histone marks across developmental stages, tissues, and species: an enhancer prediction case study

BACKGROUND: Dynamic activation and inactivation of gene regulatory DNA produce the expression changes that drive the differentiation of cellular lineages. Identifying regulatory regions active during developmental transitions is necessary to understand how the genome specifies complex developmental...

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Detalles Bibliográficos
Autor principal: Capra, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342796/
https://www.ncbi.nlm.nih.gov/pubmed/25765133
http://dx.doi.org/10.1186/s12864-015-1264-3