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Extrapolating histone marks across developmental stages, tissues, and species: an enhancer prediction case study
BACKGROUND: Dynamic activation and inactivation of gene regulatory DNA produce the expression changes that drive the differentiation of cellular lineages. Identifying regulatory regions active during developmental transitions is necessary to understand how the genome specifies complex developmental...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342796/ https://www.ncbi.nlm.nih.gov/pubmed/25765133 http://dx.doi.org/10.1186/s12864-015-1264-3 |