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Enhanced tumour cell nuclear targeting in a tumour progression model

BACKGROUND: There is an urgent need for new approaches to deliver bioactive molecules to cancer cells efficiently and specifically. METHODS: Here we fuse the cancer cell nuclear targeting module of the Chicken Anaemia Virus Apoptin protein to the core histones H2B and H3 and utilise them in transfec...

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Detalles Bibliográficos
Autores principales: Nastasie, Michael S, Thissen, Helmut, Jans, David A, Wagstaff, Kylie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342815/
https://www.ncbi.nlm.nih.gov/pubmed/25885577
http://dx.doi.org/10.1186/s12885-015-1045-z