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Enhanced tumour cell nuclear targeting in a tumour progression model
BACKGROUND: There is an urgent need for new approaches to deliver bioactive molecules to cancer cells efficiently and specifically. METHODS: Here we fuse the cancer cell nuclear targeting module of the Chicken Anaemia Virus Apoptin protein to the core histones H2B and H3 and utilise them in transfec...
Autores principales: | Nastasie, Michael S, Thissen, Helmut, Jans, David A, Wagstaff, Kylie M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342815/ https://www.ncbi.nlm.nih.gov/pubmed/25885577 http://dx.doi.org/10.1186/s12885-015-1045-z |
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