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Sustained Response of a Clivus Chordoma to Erlotinib after Imatinib Failure

Chordoma is a rare malignant axial tumour that develops from embryonic remnants of the notochord. Surgery and irradiation are the standard initial treatment. However, local recurrence is frequent and cytotoxic chemotherapy is inefficient. Transient activity of imatinib, a platelet-derived growth fac...

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Detalles Bibliográficos
Autores principales: Houessinon, Aline, Boone, Mathieu, Constans, Jean-Marc, Toussaint, Patrick, Chauffert, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342859/
https://www.ncbi.nlm.nih.gov/pubmed/25762924
http://dx.doi.org/10.1159/000371843