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Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

BACKGROUND: To evaluate whether the addition of bevacizumab (BVZ) to capecitabine-based chemoradiotherapy in the preoperative treatment of locally advanced rectal cancer (LARC) improves efficacy measured by the pathological complete response (pCR) rate. METHODS: A phase II two-step design was perfor...

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Detalles Bibliográficos
Autores principales: García, Margarita, Martinez-Villacampa, Mercedes, Santos, Cristina, Navarro, Valentin, Teule, Alex, Losa, Ferran, Pisa, Aleydis, Cambray, Maria, Soler, Gemma, Lema, Laura, Kreisler, Esther, Figueras, Agnes, Juan, Xavier San, Viñals, Francesc, Biondo, Sebastiano, Salazar, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342871/
https://www.ncbi.nlm.nih.gov/pubmed/25886275
http://dx.doi.org/10.1186/s12885-015-1052-0