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Bridger: a new framework for de novo transcriptome assembly using RNA-seq data

We present a new de novo transcriptome assembler, Bridger, which takes advantage of techniques employed in Cufflinks to overcome limitations of the existing de novo assemblers. When tested on dog, human, and mouse RNA-seq data, Bridger assembled more full-length reference transcripts while reporting...

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Detalles Bibliográficos
Autores principales: Chang, Zheng, Li, Guojun, Liu, Juntao, Zhang, Yu, Ashby, Cody, Liu, Deli, Cramer, Carole L, Huang, Xiuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342890/
https://www.ncbi.nlm.nih.gov/pubmed/25723335
http://dx.doi.org/10.1186/s13059-015-0596-2