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Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

INTRODUCTION: Epigallocatechin 3-gallate (EGCG), a polyphenol present in green tea, was shown to exert chondroprotective effects in vitro. In this study, we used a posttraumatic osteoarthritis (OA) mouse model to test whether EGCG could slow the progression of OA and relieve OA-associated pain. METH...

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Detalles Bibliográficos
Autores principales: Leong, Daniel J, Choudhury, Marwa, Hanstein, Regina, Hirsh, David M, Kim, Sun Jin, Majeska, Robert J, Schaffler, Mitchell B, Hardin, John A, Spray, David C, Goldring, Mary B, Cobelli, Neil J, Sun, Hui B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342891/
https://www.ncbi.nlm.nih.gov/pubmed/25516005
http://dx.doi.org/10.1186/s13075-014-0508-y