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MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer

INTRODUCTION: Increasing evidence indicates that microRNAs (miRNAs) are important players in oncogenesis. Considering the widespread use of aromatase inhibitors (AIs) in endocrine therapy as a first-line treatment for postmenopausal estrogen receptor α–positive breast cancer patients, identifying de...

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Detalles Bibliográficos
Autores principales: Vilquin, Paul, Donini, Caterina F, Villedieu, Marie, Grisard, Evelyne, Corbo, Laura, Bachelot, Thomas, Vendrell, Julie A, Cohen, Pascale A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342894/
https://www.ncbi.nlm.nih.gov/pubmed/25633049
http://dx.doi.org/10.1186/s13058-015-0515-1