Suberoyl bis-hydroxamic acid enhances cytotoxicity induced by proteasome inhibitors in breast cancer cells

BACKGROUND: Suberoyl bis-hydroxamic acid (SBHA) is a histone deacetylase (HDAC) inhibitor and exerts anti-growth effects in several malignancies including breast cancer. Proteasome inhibitors such as Bortezomib and MG-132 constitute novel anticancer agents. In this study, we investigated the synergi...

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Detalles Bibliográficos
Autores principales: Yang, Xinmiao, Shi, Zeliang, Zhang, Ning, Ou, Zhouluo, Fu, Shen, Hu, Xichun, Shen, Zhenzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342900/
https://www.ncbi.nlm.nih.gov/pubmed/25729327
http://dx.doi.org/10.1186/s12935-014-0107-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342900/
https://www.ncbi.nlm.nih.gov/pubmed/25729327
http://dx.doi.org/10.1186/s12935-014-0107-7

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