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Suberoyl bis-hydroxamic acid enhances cytotoxicity induced by proteasome inhibitors in breast cancer cells
BACKGROUND: Suberoyl bis-hydroxamic acid (SBHA) is a histone deacetylase (HDAC) inhibitor and exerts anti-growth effects in several malignancies including breast cancer. Proteasome inhibitors such as Bortezomib and MG-132 constitute novel anticancer agents. In this study, we investigated the synergi...
Autores principales: | Yang, Xinmiao, Shi, Zeliang, Zhang, Ning, Ou, Zhouluo, Fu, Shen, Hu, Xichun, Shen, Zhenzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342900/ https://www.ncbi.nlm.nih.gov/pubmed/25729327 http://dx.doi.org/10.1186/s12935-014-0107-7 |
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