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An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice

INTRODUCTION: The link between cardiovascular disease (CVD) and patients with chronic inflammation is not clearly understood. We examined a knock-in mouse expressing a poly-ubiquitin-binding-defective mutant of the protein ABIN1 (ABIN1(D485N)), which develops a systemic lupus erythematosus-like auto...

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Detalles Bibliográficos
Autores principales: Akbar, Naveed, Nanda, Sambit, Belch, Jill, Cohen, Philip, Khan, Faisel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342941/
https://www.ncbi.nlm.nih.gov/pubmed/25648164
http://dx.doi.org/10.1186/s13075-015-0543-3