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Principles of regulatory information conservation between mouse and human

To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors (TFs) in human–mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines. By combining the genome-wide transcription factor occupancy repe...

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Detalles Bibliográficos
Autores principales: Cheng, Yong, Ma, Zhihai, Kim, Bong-Hyun, Wu, Weisheng, Cayting, Philip, Boyle, Alan P., Sundaram, Vasavi, Xing, Xiaoyun, Dogan, Nergiz, Li, Jingjing, Euskirchen, Ghia, Lin, Shin, Lin, Yiing, Visel, Axel, Kawli, Trupti, Yang, Xinqiong, Patacsil, Dorrelyn, Keller, Cheryl A., Giardine, Belinda, The Mouse ENCODE Consortium, Kundaje, Anshul, Wang, Ting, Pennacchio, Len A., Weng, Zhiping, Hardison, Ross C., Snyder, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343047/
https://www.ncbi.nlm.nih.gov/pubmed/25409826
http://dx.doi.org/10.1038/nature13985