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Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas

BACKGROUND: The large airways of the lungs (trachea and bronchi) are lined with a pseudostratified mucociliary epithelium, which is maintained by stem cells/progenitors within the basal cell compartment. Alterations in basal cell behavior can contribute to large airway diseases including squamous ce...

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Detalles Bibliográficos
Autores principales: Van de Laar, Emily, Clifford, Monica, Hasenoeder, Stefan, Kim, Bo Ram, Wang, Dennis, Lee, Sharon, Paterson, Josh, Vu, Nancy M, Waddell, Thomas K, Keshavjee, Shaf, Tsao, Ming-Sound, Ailles, Laurie, Moghal, Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343068/
https://www.ncbi.nlm.nih.gov/pubmed/25551685
http://dx.doi.org/10.1186/s12931-014-0160-8