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A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features

BACKGROUND: Perioperatory chemoradiotherapy (CRT) improves local control and survival in patients with locally advanced rectal cancer (LARC). The objective of the current study was to evaluate the addition of bevacizumab (BEV) to preoperative capecitabine (CAP)-based CRT in LARC, and to explore biom...

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Detalles Bibliográficos
Autores principales: Salazar, Ramon, Capdevila, Jaume, Laquente, Berta, Manzano, Jose Luis, Pericay, Carles, Villacampa, Mercedes Martínez, López, Carlos, Losa, Ferran, Safont, Maria Jose, Gómez, Auxiliadora, Alonso, Vicente, Escudero, Pilar, Gallego, Javier, Sastre, Javier, Grávalos, Cristina, Biondo, Sebastiano, Palacios, Amalia, Aranda, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343271/
https://www.ncbi.nlm.nih.gov/pubmed/25886378
http://dx.doi.org/10.1186/s12885-015-1053-z