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A Human Platelet Calcium Calculator Trained by Pairwise Agonist Scanning
Since platelet intracellular calcium mobilization [Ca(t)](i) controls granule release, cyclooxygenase-1 and integrin activation, and phosphatidylserine exposure, blood clotting simulations require prediction of platelet [Ca(t)](i) in response to combinatorial agonists. Pairwise Agonist Scanning (PAS...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344206/ https://www.ncbi.nlm.nih.gov/pubmed/25723389 http://dx.doi.org/10.1371/journal.pcbi.1004118 |