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Role of Cortactin Homolog HS1 in Transendothelial Migration of Natural Killer Cells

Natural Killer (NK) cells perform many functions that depend on actin assembly, including adhesion, chemotaxis, lytic synapse assembly and cytolysis. HS1, the hematopoietic homolog of cortactin, binds to Arp2/3 complex and promotes actin assembly by helping to form and stabilize actin filament branc...

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Detalles Bibliográficos
Autores principales: Mukherjee, Suranjana, Kim, Joanna, Mooren, Olivia L., Shahan, Stefanie T., Cohan, Megan, Cooper, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344232/
https://www.ncbi.nlm.nih.gov/pubmed/25723543
http://dx.doi.org/10.1371/journal.pone.0118153