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An Integrated Approach to Reconstructing Genome-Scale Transcriptional Regulatory Networks

Transcriptional regulatory networks (TRNs) program cells to dynamically alter their gene expression in response to changing internal or environmental conditions. In this study, we develop a novel workflow for generating large-scale TRN models that integrates comparative genomics data, global gene ex...

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Detalles Bibliográficos
Autores principales: Imam, Saheed, Noguera, Daniel R., Donohue, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344238/
https://www.ncbi.nlm.nih.gov/pubmed/25723545
http://dx.doi.org/10.1371/journal.pcbi.1004103