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An Integrated Approach to Reconstructing Genome-Scale Transcriptional Regulatory Networks
Transcriptional regulatory networks (TRNs) program cells to dynamically alter their gene expression in response to changing internal or environmental conditions. In this study, we develop a novel workflow for generating large-scale TRN models that integrates comparative genomics data, global gene ex...
Autores principales: | Imam, Saheed, Noguera, Daniel R., Donohue, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344238/ https://www.ncbi.nlm.nih.gov/pubmed/25723545 http://dx.doi.org/10.1371/journal.pcbi.1004103 |
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