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Novel Mutations in K13 Propeller Gene of Artemisinin-Resistant Plasmodium falciparum

We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012–2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide c...

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Detalles Bibliográficos
Autores principales: Isozumi, Rie, Uemura, Haruki, Kimata, Isao, Ichinose, Yoshio, Logedi, John, Omar, Ahmeddin H., Kaneko, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344268/
https://www.ncbi.nlm.nih.gov/pubmed/25695257
http://dx.doi.org/10.3201/eid2103.140898