Human leukocyte telomere length is associated with DNA methylation levels in multiple subtelomeric and imprinted loci

In humans, leukocyte telomere length (LTL) is positively correlated with lifespan, and shorter LTL is associated with increased risk of age-related disease. In this study we tested for association between telomere length and methylated cytosine levels. Measurements of mean telomere length and DNA me...

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Detalles Bibliográficos
Autores principales: Buxton, Jessica L., Suderman, Matthew, Pappas, Jane J., Borghol, Nada, McArdle, Wendy, Blakemore, Alexandra I. F., Hertzman, Clyde, Power, Christine, Szyf, Moshe, Pembrey, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344300/
https://www.ncbi.nlm.nih.gov/pubmed/24828261
http://dx.doi.org/10.1038/srep04954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344300/
https://www.ncbi.nlm.nih.gov/pubmed/24828261
http://dx.doi.org/10.1038/srep04954

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