N6-Adenosine Methylation in MiRNAs

Methylation of N6-adenosine (m6A) has been observed in many different classes of RNA, but its prevalence in microRNAs (miRNAs) has not yet been studied. Here we show that a knockdown of the m6A demethylase FTO affects the steady-state levels of several miRNAs. Moreover, RNA immunoprecipitation with...

Descripción completa

Detalles Bibliográficos
Autores principales: Berulava, Tea, Rahmann, Sven, Rademacher, Katrin, Klein-Hitpass, Ludgar, Horsthemke, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344304/
https://www.ncbi.nlm.nih.gov/pubmed/25723394
http://dx.doi.org/10.1371/journal.pone.0118438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344304/
https://www.ncbi.nlm.nih.gov/pubmed/25723394
http://dx.doi.org/10.1371/journal.pone.0118438

Ejemplares similares