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Protein Sectors: Statistical Coupling Analysis versus Conservation

Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed “sectors”. The method applies spectral analysis to a matrix obtained by combining correlation information with sequence conservation. It has been...

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Detalles Bibliográficos
Autores principales: Teşileanu, Tiberiu, Colwell, Lucy J., Leibler, Stanislas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344308/
https://www.ncbi.nlm.nih.gov/pubmed/25723535
http://dx.doi.org/10.1371/journal.pcbi.1004091