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Protein Sectors: Statistical Coupling Analysis versus Conservation
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed “sectors”. The method applies spectral analysis to a matrix obtained by combining correlation information with sequence conservation. It has been...
Autores principales: | Teşileanu, Tiberiu, Colwell, Lucy J., Leibler, Stanislas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344308/ https://www.ncbi.nlm.nih.gov/pubmed/25723535 http://dx.doi.org/10.1371/journal.pcbi.1004091 |
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