Region-Specific Activation of oskar mRNA Translation by Inhibition of Bruno-Mediated Repression

A complex program of translational repression, mRNA localization, and translational activation ensures that Oskar (Osk) protein accumulates only at the posterior pole of the Drosophila oocyte. Inappropriate expression of Osk disrupts embryonic axial patterning, and is lethal. A key factor in transla...

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Detalles Bibliográficos
Autores principales: Kim, Goheun, Pai, Chin-I, Sato, Keiji, Person, Maria D., Nakamura, Akira, Macdonald, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344327/
https://www.ncbi.nlm.nih.gov/pubmed/25723530
http://dx.doi.org/10.1371/journal.pgen.1004992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344327/
https://www.ncbi.nlm.nih.gov/pubmed/25723530
http://dx.doi.org/10.1371/journal.pgen.1004992

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