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Region-Specific Activation of oskar mRNA Translation by Inhibition of Bruno-Mediated Repression
A complex program of translational repression, mRNA localization, and translational activation ensures that Oskar (Osk) protein accumulates only at the posterior pole of the Drosophila oocyte. Inappropriate expression of Osk disrupts embryonic axial patterning, and is lethal. A key factor in transla...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344327/ https://www.ncbi.nlm.nih.gov/pubmed/25723530 http://dx.doi.org/10.1371/journal.pgen.1004992 |