Allele-specific copy number profiling by next-generation DNA sequencing

The progression and clonal development of tumors often involve amplifications and deletions of genomic DNA. Estimation of allele-specific copy number, which quantifies the number of copies of each allele at each variant loci rather than the total number of chromosome copies, is an important step in...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Bell, John M., Zavala, Nicolas A., Ji, Hanlee P., Zhang, Nancy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344483/
https://www.ncbi.nlm.nih.gov/pubmed/25477383
http://dx.doi.org/10.1093/nar/gku1252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344483/
https://www.ncbi.nlm.nih.gov/pubmed/25477383
http://dx.doi.org/10.1093/nar/gku1252

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