Molecular mechanisms in DM1 — a focus on foci

Myotonic dystrophy type 1 is caused by abnormal expansion of a CTG-trinucleotide repeat in the gene encoding Dystrophia Myotonica Protein Kinase (DMPK), which in turn leads to global deregulation of gene expression in affected individuals. The transcribed mRNA contains a massive CUG-expansion in the...

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Detalles Bibliográficos
Autores principales: Pettersson, Olof Joakim, Aagaard, Lars, Jensen, Thomas Gryesten, Damgaard, Christian Kroun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344492/
https://www.ncbi.nlm.nih.gov/pubmed/25605794
http://dx.doi.org/10.1093/nar/gkv029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344492/
https://www.ncbi.nlm.nih.gov/pubmed/25605794
http://dx.doi.org/10.1093/nar/gkv029

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