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Luzp4 defines a new mRNA export pathway in cancer cells

Cancer testis antigens (CTAs) represented a poorly characterized group of proteins whose expression is normally restricted to testis but are frequently up-regulated in cancer cells. Here we show that one CTA, Luzp4, is an mRNA export adaptor. It associates with the TREX mRNA export complex subunit U...

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Detalles Bibliográficos
Autores principales: Viphakone, Nicolas, Cumberbatch, Marcus G., Livingstone, Michaela J., Heath, Paul R., Dickman, Mark J., Catto, James W., Wilson, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344508/
https://www.ncbi.nlm.nih.gov/pubmed/25662211
http://dx.doi.org/10.1093/nar/gkv070