Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

The function of RNA is subtly modulated by post-transcriptional modifications. Here, we report an important crosstalk in the covalent modification of two classes of RNAs. We demonstrate that yeast Kre33 and human NAT10 are RNA cytosine acetyltransferases with, surprisingly, specificity toward both 1...

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Detalles Bibliográficos
Autores principales: Sharma, Sunny, Langhendries, Jean-Louis, Watzinger, Peter, Kötter, Peter, Entian, Karl-Dieter, Lafontaine, Denis L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344512/
https://www.ncbi.nlm.nih.gov/pubmed/25653167
http://dx.doi.org/10.1093/nar/gkv075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344512/
https://www.ncbi.nlm.nih.gov/pubmed/25653167
http://dx.doi.org/10.1093/nar/gkv075

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