Cargando…

Complementation of aprataxin deficiency by base excision repair enzymes

Abortive ligation during base excision repair (BER) leads to blocked repair intermediates containing a 5′-adenylated-deoxyribose phosphate (5′-AMP-dRP) group. Aprataxin (APTX) is able to remove the AMP group allowing repair to proceed. Earlier results had indicated that purified DNA polymerase β (po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Çağlayan, Melike, Horton, Julie K., Prasad, Rajendra, Wilson, Samuel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344515/ https://www.ncbi.nlm.nih.gov/pubmed/25662216 http://dx.doi.org/10.1093/nar/gkv079

Ejemplares similares

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts
por: Çağlayan, Melike, et al.
Publicado: (2017)

Rev1 is a base excision repair enzyme with 5′-deoxyribose phosphate lyase activity
por: Prasad, Rajendra, et al.
Publicado: (2016)

Pol β associated complex and base excision repair factors in mouse fibroblasts
por: Prasad, Rajendra, et al.
Publicado: (2012)

Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro
por: Prasad, Rajendra, et al.
Publicado: (2009)

DNA(3′)pp(5′)G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition
por: Chauleau, Mathieu, et al.
Publicado: (2015)

Specialization of an Exonuclease III family enzyme in the repair of 3′ DNA lesions during base excision repair in the human pathogen Neisseria meningitidis
por: Silhan, Jan, et al.
Publicado: (2012)

Participation of RecJ in the base excision repair pathway of Deinococcus radiodurans
por: Cheng, Kaiying, et al.
Publicado: (2020)

Structural basis for recognition and repair of the 3′-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis
por: Silhan, Jan, et al.
Publicado: (2018)

A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine
por: Ponferrada-Marín, María Isabel, et al.
Publicado: (2011)

Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates
por: Wong, Heng-Kuan, et al.
Publicado: (2007)

Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair
por: Li, Ya-Qiang, et al.
Publicado: (2007)

Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases
por: Woods, Ryan D., et al.
Publicado: (2016)

Identification of a conserved 5′-dRP lyase activity in bacterial DNA repair ligase D and its potential role in base excision repair
por: de Ory, Ana, et al.
Publicado: (2016)

The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway
por: Rudolf, Jana, et al.
Publicado: (2010)

The ATPase mechanism of UvrA(2) reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair
por: Case, Brandon C, et al.
Publicado: (2019)

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity
por: Hohl, Marcel, et al.
Publicado: (2007)

Human DNA polymerase β polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity
por: Guo, Zhigang, et al.
Publicado: (2009)

Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase
por: Bernstein, N. K., et al.
Publicado: (2009)

Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA
por: Horton, John R., et al.
Publicado: (2014)

Structures and activities of archaeal members of the LigD 3′-phosphoesterase DNA repair enzyme superfamily
por: Smith, Paul, et al.
Publicado: (2011)

Interfering with nucleotide excision by the coronavirus 3′-to-5′ exoribonuclease
por: Chinthapatla, Rukesh, et al.
Publicado: (2022)

The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase β in long patch base excision repair
por: Gembka, Agnieszka, et al.
Publicado: (2007)

USER™ friendly DNA engineering and cloning method by uracil excision
por: Bitinaite, Jurate, et al.
Publicado: (2007)

Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities
por: Fukuyo, Masaki, et al.
Publicado: (2015)

Structural insights to the metal specificity of an archaeal member of the LigD 3′-phosphoesterase DNA repair enzyme family
por: Das, Ushati, et al.
Publicado: (2012)

AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP
por: Hartl, Maximilian J., et al.
Publicado: (2008)

DNA polymerase β contains a functional nuclear localization signal at its N-terminus
por: Kirby, Thomas W., et al.
Publicado: (2017)

The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
por: Guan, Xin, et al.
Publicado: (2007)

In vitro selection of DNA-cleaving deoxyribozyme with site-specific thymidine excision activity
por: Wang, Mingqi, et al.
Publicado: (2014)

Signature motifs of GDP polyribonucleotidyltransferase, a non-segmented negative strand RNA viral mRNA capping enzyme, domain in the L protein are required for covalent enzyme–pRNA intermediate formation
por: Neubauer, Julie, et al.
Publicado: (2016)

Identification of a residue critical for the excision of 3′-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family
por: Castillo-Acosta, Víctor M., et al.
Publicado: (2009)

Functional complementation of UvsX and UvsY mutations in the mediation of T4 homologous recombination
por: Farb, Joshua N., et al.
Publicado: (2009)

A sensor complements the steric gate when DNA polymerase ϵ discriminates ribonucleotides
por: Parkash, Vimal, et al.
Publicado: (2023)

Nucleobase modification by an RNA enzyme
por: Poudyal, Raghav R., et al.
Publicado: (2017)

C-terminal lysine repeats in Streptomyces topoisomerase I stabilize the enzyme–DNA complex and confer high enzyme processivity
por: Strzałka, Agnieszka, et al.
Publicado: (2017)

Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine
por: Wang, Hua, et al.
Publicado: (2011)

The wobble nucleotide-excising anticodon nuclease RloC is governed by the zinc-hook and DNA-dependent ATPase of its Rad50-like region
por: Klaiman, Daniel, et al.
Publicado: (2012)

Excision-reintegration at a pneumococcal phase-variable restriction-modification locus drives within- and between-strain epigenetic differentiation and inhibits gene acquisition
por: Kwun, Min Jung, et al.
Publicado: (2018)

Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages
por: Olorunniji, Femi J., et al.
Publicado: (2015)

Atomic force microscopy of the EcoKI Type I DNA restriction enzyme bound to DNA shows enzyme dimerization and DNA looping
por: Neaves, Kelly J., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_sukcv8d531ecci71popruk1k93