Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH

Current methods for characterizing extrachromosomal nuclear DNA in mammalian cells do not permit single-cell analysis, are often semi-quantitative and frequently biased toward the detection of circular species. To overcome these limitations, we developed Halo-FISH to visualize and quantitatively ana...

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Detalles Bibliográficos
Autores principales: Komosa, Martin, Root, Heather, Meyn, M. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344523/
https://www.ncbi.nlm.nih.gov/pubmed/25662602
http://dx.doi.org/10.1093/nar/gkv091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344523/
https://www.ncbi.nlm.nih.gov/pubmed/25662602
http://dx.doi.org/10.1093/nar/gkv091

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