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Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH
Current methods for characterizing extrachromosomal nuclear DNA in mammalian cells do not permit single-cell analysis, are often semi-quantitative and frequently biased toward the detection of circular species. To overcome these limitations, we developed Halo-FISH to visualize and quantitatively ana...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344523/ https://www.ncbi.nlm.nih.gov/pubmed/25662602 http://dx.doi.org/10.1093/nar/gkv091 |