Autonomous actions of the human growth hormone long-range enhancer

The human growth hormone (hGH) gene is controlled by a long-range enhancer, HSI, located 14.5 kb 5′ to the hGH promoter. HSI establishes a domain of noncoding transcription that is ‘looped’ to the hGH promoter as an essential step in initiating hGH gene expression. Thus, defining how HSI generates i...

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Detalles Bibliográficos
Autores principales: Yoo, Eung Jae, Brown, Christopher D., Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344525/
https://www.ncbi.nlm.nih.gov/pubmed/25662214
http://dx.doi.org/10.1093/nar/gkv093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344525/
https://www.ncbi.nlm.nih.gov/pubmed/25662214
http://dx.doi.org/10.1093/nar/gkv093

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