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Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosa

The Type I-F CRISPR-mediated (clustered regularly interspaced short palindromic repeats) adaptive immune system in Pseudomonas aeruginosa consists of two CRISPR loci and six CRISPR-associated (cas) genes. Foreign DNA surveillance is performed by a complex of Cas proteins (Csy1–4) that assemble with...

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Detalles Bibliográficos
Autores principales: Rollins, MaryClare F., Schuman, Jason T., Paulus, Kirra, Bukhari, Habib S.T., Wiedenheft, Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344526/
https://www.ncbi.nlm.nih.gov/pubmed/25662606
http://dx.doi.org/10.1093/nar/gkv094